Corrigendum to “Monomeric C-reactive protein regulates fibronectin mediated monocyte adhesion” [Mol. Immunol. 117 (2020) 122–130]
نویسندگان
چکیده
منابع مشابه
Perplexity of monocyte responses to C-reactive protein (CRP).
Thromb Haemost 2008; 99: 461–462 C-reactive protein (CRP), a member of the pentraxin family, is one of the prototypic plasma biomarkers of inflammation (1, 2). The physiological roles of CRP in the innate immune response have, however, remained elusive as it possesses both proand anti-inflammatory actions (1, 2). Inflammation is pivotal in all phases of atherosclerosis from the nascent lesion t...
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C-reactive protein, a member of the pentraxin superfamily, is a prototypical ‘acute-phase’ protein that is synthesized at a low rate under physiological conditions but is markedly induced and secreted following tissue injury and inflammation. Rapid secretion of C-reactive protein during the acute-phase response results in up to 1000-fold increases in plasma levels within 24–48 h. As a result, C...
متن کاملMonomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin.
Previous studies have shown that complement activation on renal tubular cells is involved in the induction of interstitial fibrosis and cellular injury. Evidence suggests that the tubular cell damage is initiated by the alternative pathway (AP) of complement with properdin having an instrumental role. Properdin is a positive regulator of the AP, which can bind necrotic cells as well as viable p...
متن کاملSignal Regulatory Protein α Negatively Regulates β2 Integrin-Mediated Monocyte Adhesion, Transendothelial Migration and Phagocytosis
BACKGROUND Signal regulate protein alpha (SIRPalpha) is involved in many functional aspects of monocytes. Here we investigate the role of SIRPalpha in regulating beta(2) integrin-mediated monocyte adhesion, transendothelial migration (TEM) and phagocytosis. METHODOLOGY/PRINCIPAL FINDINGS THP-1 monocytes/macropahges treated with advanced glycation end products (AGEs) resulted in a decrease of ...
متن کاملActivation of human monocyte tumoricidal activity by C-reactive protein.
We examined the effect of purified human C-reactive protein (CRP) on induction of human peripheral blood monocyte (Mo)-mediated cytotoxicity (CTX) and oxidative metabolism. Exposure of Mo to acute phase serum levels of CRP in vitro resulted in dose-dependent expression of CTX against human tumor cell lines. Nonneoplastic human fibroblasts and glial cells were not affected by CRP-exposed Mo, and...
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ژورنال
عنوان ژورنال: Molecular Immunology
سال: 2020
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2020.06.001